Structure, Function and Regulation

نویسندگان

  • Steven J. D. Karlish
  • Daniel. M. Tal
  • Rivka Goldshleger
  • Eytan Cohen
  • Maria Füzesi
  • Moshit Lindzen
  • Yael Lifshitz
  • Talya Belogus
  • Haim Haviv
  • Elizabeta Dinitz
چکیده

The Na/K-ATPase or Na, K-pump utilizes the free energy of hydrolysis of ATP to actively transport Na and K ions across mammalian cell membranes. This function underlies essentially all of mammalian cell physiology. For example, in the kidney the Na, K-pump controls body Na and K balance, extracellular volume and blood pressure. The Na/K-ATPase is the receptor of digitalis steroids used to treat heart failure.

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تاریخ انتشار 2006